Breeding programs generate large numbers of non-coding sequence variants from GWAS studies, TILLING banks or editing campaigns near PAM sites. The challenge is knowing which ones functionally affect gene expression before investing in field follow up. Annogen’s SuRE™ platform screens thousands of variants in parallel directly in relevant plant cell systems, delivering a prioritized shortlist with experimentally validated functional effects.
Test thousands of non-coding variants associated with a trait of interest to identify which ones actually affect gene regulation before investing in field validation.
Screen variants from EMS seedbanks to determine which affect expression of relevant pathway genes, enabling more targeted selection from existing germplasm.
Test the functional impact of specific deletions or substitutions near PAM sites in parallel, before committing to plant transformation.
Let’s start with your biological system.
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